- Jair Bolsonaro begins his four-year term as President of Brazil.
- Unmanned space probe New Horizons makes a close approach of the Kuiper belt object (KBO) 486958 Arrokoth at 05:33 UTC.
- Qatar withdraws from OPEC.
- Chinese probe Chang’e 4 becomes the first human-made object to land on the far side of the Moon.
- Venezuela enters a constitutional crisis as Juan Guaidó and the National Assembly declare incumbent President Nicolás Maduro “illegitimate” and start the process of attempting to remove him.
- 16 central committee members of Bibeksheel Sajha Party leave to form a new party.
- The U.S. Justice Department charges Chinese tech firm Huawei with multiple counts of fraud, raising U.S.–China tensions.
- Pope Francis arrives in Abu Dhabi, United Arab Emirates, becoming the first pope to visit the Arabian Peninsula.
- A suicide bomb attack on a vehicle convoy in Indian-administered Kashmir kills at least 40 Indian security personnel, making it the deadliest attack on India’s security personnel in Kashmir in three decades.
- Commission for the Investigation of Abuse of Authority commissioner Raj Narayan Pathak resigns.
- SpaceIL launches the Beresheet probe, the world’s first privately financed mission to the Moon.
- The Indian Air Force launches airstrikes on purported militant camps in Balakot, Pakistan.
- Minister of Culture, Tourism Culture and Civil Aviation Rabindra Adhikari is among 7 killed in a helicopter crash.
- Ethiopian Airlines Flight 302, a Boeing 737 MAX 8 bound for Nairobi, crashes shortly after takeoff from Addis Ababa killing all 157 people on board. All Boeing 737 MAX aircraft are subsequently grounded worldwide.
- 51 people are killed and 50 others injured in terrorist attacks on two mosques in Christchurch, New Zealand.
- Europe’s antitrust regulators fine Google 1.49 billion euros ($1.7 billion) for freezing out rivals in the online advertising business.
- An estimated 400,000 people march in central London in protest against Brexit.
- Nepal Investment summit held in Kathmandu.
- A tornado kills 28 people in Parsa and Bara. It is the first verified record of a tornado event in Nepal.
- Scientists from the Event Horizon Telescope project announce the first ever image of a black hole, located in the centre of the M87 galaxy.
- WikiLeaks co-founder Julian Assange is arrested after seven years in Ecuador’s embassy in London.
- The 2019 Indian general election begins.
- A Summit Air Let L-410 Turbolet veers off the runway during takeoff at Lukla Airport, impacting a helicopter and killing 3 including the co-pilot.
- NepaliSat-1 is launched. It is Nepal’s first ever research satellite to be sent into space.
- A series of bomb attacks occur at eight locations in Sri Lanka, including three churches, four hotels and one housing complex in Colombo, on Easter Sunday, leaving 259 people dead and over 500 injured.
- Avengers: Endgame is released in theaters, breaking many box-office records, including becoming the highest grossing movie of all time.
- Birth of Archie Mountbatten-Windsor, first child of the Duke and Duchess of Sussex and seventh in the line of succession to the British throne
- Taiwan’s parliament becomes the first in Asia to legalise same-sex marriage.
- China–United States trade war: Google pulls Android update support for Huawei phones, as well as the Google Play Store and Gmail apps, after the Chinese technology company was blacklisted by the United States.
- 2019 Indian general election: Narendra Modi secures a landslide win, with his party BJP alone gaining 303 of the 543 seats in parliament, and his political alliance winning 353 seats of the 543.
- The 2019 Cricket World Cup is held in England and Wales.
- Pranesh Gautam, an youtuber, is arrested for his satirical review of the Bir Bikram 2 on the YouTube channel meme Nepal.
- 2019 Hong Kong anti-extradition bill protests: Over 1 million people in Hong Kong protest against proposed legislation regarding extradition to China. It is the largest protest in Hong Kong since the 1997 handover.
- Government withdraws the Guthi Bill tabled in the upper house, ahead of a protest gathering announced for the following day.
- The European Parliament elects Ursula von der Leyen as the new President of the European Commission. She is the first female to be elected to this office in EU history.
- The World Health Organization (WHO) declares the Kivu Ebola epidemic to be a public health emergency of international concern.
- 36 people are killed and more than 30 others injured after an arson attack at an animation company in Kyoto, Japan.
- Boris Johnson becomes Prime Minister of the United Kingdom.
- India bans triple talaq.
- Revocation of the special status of Jammu and Kashmir: India revokes the part of its constitution that gives Indian-administered Kashmir special status in an unprecedented move.
- Sushma Swaraj death.
- 2019 Indian floods: At least 114 people, including 57 in Kerala, 30 in Karnataka and 27 in Maharashtra, are reported to have died in monsoon-related floods in India. At least 227 died across India, Nepal, Bangladesh and Pakistan.
- 2019 Amazon rainforest wildfires: Brazil’s National Institute for Space Research (INPE) reports fires burning in the Amazon rainforest at a record rate, with more than 36,000 in the year to date, while smoke reaches São Paulo more than 1,700 miles (2,700 km) away.
- Death of Robert Mugabe
- Chandrayaan-2, India’s second lunar probe, was successful to put the orbit in lunar orbit, but the lander Vikram crashes into the surface of the moon.
- Astronomers announce the detection of water in the atmosphere of exoplanet K2-18b, the first such discovery for an exoplanet in the habitable zone around a star.
- One of the largest and oldest travel firms, Thomas Cook, goes bankrupt as last-minute rescue negotiations fail, stranding 600,000 tourists worldwide.
- 500,000 people march in a climate change protest led by activist Greta Thunberg and Prime Minister Justin Trudeau in Montreal, Canada.4,000,000 go on strike around the world.
- Speaker of the House of Representatives Krishna Bahadur Mahara resigns after being accused of rape by a female staff of Parliament.
- Chinese President and General Secretary of the Communist Party Xi Jinping arrives on a two-day state visit at the invitation of President Bidhya Devi Bhandari.
- House of Representative member Mohammad Aftab Alam of Nepali Congress is arrested in connection with an explosion and the subsequent murder of at least 23 persons in Rautahat in 2008.
- NASA astronauts Jessica Meir and Christina Koch conduct the first all-female spacewalk outside of the International Space Station.
- An estimated one million people march through London in a protest organised by People’s Vote, to demand a second referendum on Brexit.
- Rapper VTEN is arrested for controversial lyrics in his song Hami Yestai Ta Ho Ni Bro.
- Social media website Twitter bans all political advertising worldwide.
- The Supreme Court of India awards a holy site in Ayodhya, Uttar Pradesh to Hindus, rejecting a Muslim claim.
- Prime Minister K.P Oli convenes an all party meeting to discuss the release of a new political map by India that depicts the disputed Kalapani within India’s border.
- Public impeachment hearings against U.S. President Donald Trump begin in the House of Representatives.
- Italy declares a state of emergency in Venice following record flooding.
- Google enters the video game market with the launch of Stadia.
- By-election for vacant seats in Federal Parliament, Provincial Assembly and Local level takes place.
- 2019 South Asian Games begins with an inauguration ceremony in Kathmandu. (December 1- December 10)
- Sanna Marin, at the age of 34, becomes the world’s youngest serving prime minister after being selected to lead Finland’s Social Democratic Party.
- The U.S. House of Representatives approves two articles of impeachment against President Trump, making him the third president to be impeached in the nation’s history.
- The CHEOPS space telescope, whose mission is to study the formation of extra-solar planets and determine their precise radius, likely density and internal structure, is launched.
- An annular solar eclipse was visible from South Asia.